SEENERGIE
Unleash Human Potential
Tesamorelin
Stimulates the release of growth hormones to reduce abdominal fat, improve recovery time, and repair tissues.
Active ingredient:
GHRH Receptor Agonist
Molecular formula:
C211H366N72O67S1
Molecular weight:
5,000.72 g/mol
Intake:
Injection
Tesamorelin
Active ingredient:
GHRH Receptor Agonist
Molecular formula:
C211H366N72O67S1
Molecular weight:
5,000.72 g/mol
Intake:
Injection
What is
Tesamorelin
Tesamorelin is a synthetic peptide hormone used to promote weight loss and reduce the accumulation of abdominal fat. It works by increasing the production of growth hormone in the body, which has been shown to help reduce the amount of fat stored in the abdominal region.
Tesamorelin acts as a potent agonist of the growth hormone-releasing hormone (GHRH) receptor, which is found in the pituitary gland. The pituitary gland is a small but crucial endocrine gland located at the base of the brain, and is responsible for the regulation of several hormones in the body, including growth hormone. By stimulating the GHRH receptor, tesamorelin increases the production of growth hormone in the body, leading to a reduction in the amount of abdominal fat stored.
In clinical studies, tesamorelin has been shown to be effective in reducing abdominal fat and improving the body’s shape in individuals with HIV-associated lipodystrophy. However, its use for weight loss and reduction of abdominal fat has also been investigated in other populations, including those without HIV.
Benefits
- Lowering triglyceride levels
- Enhancing cognitive function in individuals over 60 years of age
- Increasing IGF-1 production
- Reducing carotid intima media size (cIMT)
- Diminishing visceral adipose tissue (VAT)
Protocols
- Content and Potency
Provided as a 10mg lyophilized vial
- Suggested Dosage
- Initiation: Tesamorelin therapy is initiated to enhance growth hormone secretion and support various metabolic processes.
- Initial Dose: Begin with 0.5 mg (0.05 ml or 5 units) subcutaneously 5 days per week (5/7 days) for the first two weeks, administered while fasting 2-3 hours prior to injection.
- Titration: If well tolerated, increase the dose to 1 mg (0.1 ml or 10 units) subcutaneously 5 days per week (5/7 days) after the initial two-week period.
- Maintenance: Maintain the dose at 1 mg (0.1 ml or 10 units) subcutaneously 5 days per week for ongoing support in growth hormone secretion and metabolic enhancement.
- Duration:Tesamorelin is administered five days per week.
- Weeks 1-2: 0.5 mg (0.05 ml or 5 units) of Tesamorelin 5 days per week
- Week 3 and onwards: 1 mg (0.1 ml or 10 units) of Tesamorelin 5 days per week
*The dosage of Tesamorelin may be adjusted based on the individual’s response, medical history, and specific treatment goals.
- Restrictions
- Known hypersensitivity to Tesamorelin or any component of the formulation.
- Not recommended for individuals with active malignancy, pregnancy, or breastfeeding.
- Caution in patients with pituitary gland issues or diabetes.
- Requirements
- Regular monitoring of growth hormone levels and metabolic parameters to assess the effectiveness of the treatment.
- Periodic blood tests to check for any adverse effects and to adjust the treatment as necessary.
Procedure
- Tesamorelin
Reconstitution
- Draw 1 ml of sterile water into a syringe.
- Inject the sterile water into a vial containing 10 mg of Tesamorelin peptide.
- Gently swirl the vial until the peptide is fully dissolved.
- Administration
- Remove the cap from a tuberculin syringe.
- Draw the reconstituted Tesamorelin solution into the syringe to the required dosage (0.05 ml or 5 units initially, 0.1 ml or 10 units after titration).
- Clean the selected injection site with an alcohol swab.
- Pinch the sanitized skin and insert the needle at a 90-degree angle.
- Administer the injection subcutaneously.
- Administer while fasting, 2-3 hours prior to injection.
- For next usage
- Store the remaining Tesamorelin solution in the refrigerator at 2-8°C.
- Before the next use, clean the vial top with an alcohol swab.
- Use a new syringe for each administration.
- Ensure to rotate injection sites (abdomen, thigh, or upper arm) to minimize skin irritation.
Clinical Research
Study:
Tesamorelin for Weight Loss
Source:
Journal of Endocrinology & Metabolism, Peptide Basics, Peptides Institute
Results:
Tesamorelin, a synthetic analog of growth hormone-releasing hormone (GHRH), has demonstrated significant potential in promoting weight loss, particularly by reducing visceral adipose tissue (VAT). Clinical trials have shown that Tesamorelin effectively targets and reduces VAT, which is a major contributor to obesity-related health issues.
In a randomized, placebo-controlled trial involving patients with type 2 diabetes, Tesamorelin treatment resulted in significant reductions in body weight and VAT. Participants experienced improvements in body composition, including reductions in waist circumference and body fat percentage. Additionally, Tesamorelin improved metabolic parameters such as insulin sensitivity, fasting glucose, and lipid profiles (total cholesterol, LDL cholesterol, HDL cholesterol, and triglycerides).
The trial also highlighted Tesamorelin’s favorable safety profile, with most adverse effects being mild and transient, including injection site reactions and occasional muscle pain. Importantly, there were no serious adverse events, indicating that Tesamorelin is well-tolerated.
Spooner LM, Olin JL, 2012, PLOS ONE, 2023,Peptides Institute, 2023
Read More: https://doi.org/10.1345/aph.1Q629, https://doi.org/10.1371/journal.pone.0179538, https://www.peptidesinstitute.org
Articles
Tesamorelin Dosage for Fat Loss
Tesamorelin dosage plays a crucial role in addressing fat loss by targeting specific growth hormone pathways. Tesamorelin, a synthetic form of growth hormone-releasing hormone (GHRH), works by stimulating the production and release of growth hormone from the pituitary gland. This helps the body metabolize fats and build lean muscle mass.
Tesamorelin Peptide Dosage for Weight Loss and Bodybuilding
Tesamorelin is a 44-amino-acid long peptide that was created as a synthetic analog of growth hormone-releasing hormone (GHRH), which is normally produced in the hypothalamus. It stimulates the pituitary gland in your brain to increase your body’s natural production of growth hormone (GH).
Doctor's Reviews
What you need to know about Tesamorelin Peptide | Peptide | San Diego Wellness Lounge
Tesamorelin is a synthetic peptide that was originally developed to treat HIV-associated lipodystrophy, a condition in which fat accumulates abnormally in certain parts of the body. It works by stimulating the production of growth hormone-releasing hormone (GHRH), which leads to increased levels of growth hormone in the body.
How Effective Is Tesamorelin? | The Power of Peptides | Dr. Matt Chalmers | Joey Thurman
As you may have heard already, peptides are a popular performance-enhancing aid in the bodybuilding community. And tesamorelin is one of the most popular growth hormone secretagogues (GHS) among, well, bodybuilders and even athletes who want to enhance their body composition in no time.
