SEENERGIE
Unleash Human Potential
Ipamorelin
Primarily used in sports medicine for its benefits in body-buliding, anti-aging, and improving recovery time.
Active ingredient:
Ipamorelin acetate
Molecular formula:
C38H49N9O5
Molecular weight:
711.863 g/mol
Intake:
Injection
Ipamorelin
Active ingredient:
Ipamorelin acetate
Molecular formula:
C38H49N9O5
Molecular weight:
711.863 g/mol
Intake:
Injection
What is
Ipamorelin
Ipamorelin is a synthetic peptide that acts as a growth hormone secretagogue, meaning it stimulates the release of growth hormone from the pituitary gland. It is a pentapeptide composed of five amino acids: Aib-His-D-2-Nal-D-Phe-Lys-NH2.
Ipamorelin works by binding to specific receptors in the pituitary gland called growth hormone secretagogue receptors (GHSRs), which triggers the release of growth hormone. Unlike other growth hormone-releasing peptides, Ipamorelin does not stimulate the release of cortisol or prolactin, which can have negative effects on the body.
Ipamorelin is primarily used for its potential therapeutic benefits in the fields of sports medicine, bodybuilding, and anti-aging. It has been shown to increase muscle mass, improve recovery time after exercise, and reduce body fat. It may also have neuroprotective effects and has been studied for its potential in the treatment of certain medical conditions, such as growth hormone deficiency and osteoporosis.
Benefits
- Improve sleep quality
- Increase bone density
- Increase muscle mass
- Improve skin elasticity
- Regenerate nerve tissues
- Strengthen the immune system
- Improve memory and memory
Protocols
- Content and Potency
Provided as a 5mg lyophilized vial
- Suggested Dosage
- Initiation: Ipamorelin therapy is initiated to stimulate growth hormone release, support muscle growth, and enhance overall recovery by mimicking the action of ghrelin.
- Initial Dose: Begin with 100 mcg (0.04 ml or 4 units) subcutaneously 5 days per week (5/7 days) while fasting 2-3 hours prior to injection for the first two weeks to assess tolerance and minimize potential side effects.
- Titration: If well tolerated, increase the dose to 200 mcg (0.08 ml or 8 units) subcutaneously 5 days per week (5/7 days) while fasting 2-3 hours prior to injection after the initial two-week period.
- Maintenance: Maintain the dose at 100-200 mcg (0.04-0.08 ml or 4-8 units) subcutaneously 5 days per week for ongoing support in growth hormone stimulation and overall recovery.
- Duration: Ipamorelin is administered five days per week.
- Weeks 1-2: 100 mcg (0.04 ml or 4 units) of Ipamorelin 5 days per week
- Week 3 and onwards: 100-200 mcg (0.04-0.08 ml or 4-8 units) of Ipamorelin 5 days per week
*Provided as a standard protocol, dose may vary depending on the condition of the patient.
*The dosage of Ipamorelin may be adjusted based on the individual’s response, medical history, and specific treatment goals.
- Restrictions
- Known hypersensitivity to Ipamorelin or any component of the formulation.
- Not recommended for use during pregnancy or breastfeeding unless specifically advised by a healthcare provider.
- Patients with a history of cancer should consult with their healthcare provider before starting this treatment, as growth hormone can influence tumor growth.
- Avoid taking other supplements or medications that might interact with Ipamorelin without professional advice.
- Requirements
- Regular monitoring of growth hormone levels and overall health to assess the effectiveness of the treatment.
- Periodic assessments to check for any adverse effects and to adjust the treatment as necessary.
- Consultation with a healthcare professional before starting Ipamorelin to ensure it is appropriate for the patient’s health condition.
- Patients should maintain a healthy lifestyle, including proper diet and exercise, to support the effectiveness of the treatment.
Procedure
- Ipamorelin
Reconstitution
- Draw 2 ml of sterile water for injection into a syringe.
- Inject the sterile water into a vial containing 5 mg of Ipamorelin peptide.
- Gently swirl the vial until the peptide is fully dissolved.
- Administration
- Remove the cap from a tuberculin syringe.
- Draw the reconstituted Ipamorelin solution into the syringe to the required dosage (0.04 ml or 4 units initially, 0.08 ml or 8 units after titration).
- Clean the selected injection site with an alcohol swab.
- Pinch the sanitized skin and insert the needle at a 90-degree angle.
- Administer the injection subcutaneously while fasting, 2-3 hours prior to injection.
- For next usage
- Store the remaining Ipamorelin solution in the refrigerator at 2-8°C.
- Before the next use, clean the vial top with an alcohol swab.
- Use a new syringe for each subcutaneous administration.
- Ensure to rotate injection sites (abdomen, thigh, or upper arm) to minimize skin irritation.
- Monitor for any unusual symptoms and report them to a healthcare provider immediately.
Clinical Research
Study:
Ipamorelin for Growth Hormone Release and Muscle Growth
Source:
European Journal of Endocrinology, Peptides.org, Muscle and Brawn
Results:
Ipamorelin is a synthetic pentapeptide that acts as a growth hormone-releasing peptide (GHRP). It is highly selective for stimulating the release of growth hormone (GH) without significantly affecting cortisol or prolactin levels. This selectivity makes Ipamorelin particularly effective for promoting muscle growth, enhancing fat loss, and improving overall body composition.
Ipamorelin works by binding to the growth hormone secretagogue receptor (GHSR-1a) in the pituitary gland. This interaction stimulates the release of GH, which then promotes anabolic processes such as muscle growth, fat metabolism, and improved recovery from exercise. Unlike other GHRPs, Ipamorelin does not significantly increase adrenocorticotropic hormone (ACTH) or cortisol levels, minimizing the risk of stress-related side effects.
Studies have demonstrated that Ipamorelin effectively increases lean muscle mass by enhancing protein synthesis and promoting muscle cell growth. In clinical trials, subjects experienced significant improvements in muscle strength and size.Ipamorelin helps reduce body fat by increasing lipolysis, the breakdown of fat stores, and enhancing the body’s metabolic rate. Participants in studies reported reductions in fat mass, particularly when combined with regular exercise and a healthy diet.The peptide aids in quicker recovery from injuries by promoting tissue repair and reducing inflammation. It also enhances collagen synthesis, which is beneficial for joint and connective tissue health. Ipamorelin improves sleep quality by promoting deeper, more restful sleep cycles. This is important for recovery and overall health, as growth hormone is primarily released during sleep.
European Journal of Endocrinology, 1998; Peptides.org, 2023; Muscle and Brawn, 2023.
Read More: https://academic.oup.com/ejendo, https://www.peptides.org/, https://www.muscleandbrawn.com/
Articles
Ipamorelin, the first selective growth hormone secretagogue
The development and pharmacology of a new potent growth hormone (GH) secretagogue, ipamorelin, is described. Ipamorelin is a pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2), which displays high GH releasing potency and efficacy in vitro and in vivo. As an outcome of a major chemistry programme, ipamorelin was identified within a series of compounds lacking the central dipeptide Ala-Trp of […]
Ipamorelin, a new growth-hormone-releasing peptide, induces longitudinal bone growth in rats
Ipamorelin is a new and potent synthetic pentapeptide which has distinct and specific growth hormone (GH)-releasing properties. With the objective of investigating the effects on longitudinal bone growth rate (LGR), body weight (BW), and GH release, ipamorelin in different doses (0, 18, 90 and 450 μg/day) was injected s.c. three times daily for 15 days […]
Doctor's Reviews
CJC-1295/Ipamorelin: Benefits, Dosage, & Side Effects | EVOLVE BHRT Telemedicine
CJC-1295/Ipamorelin are growth hormone peptides that may help to burn fat, recover from exercise faster, and improve sleep quality. Learn more about the benefits, typical dosage, and side effects of CJC-1295/Ipamorelin with Justin Hokams, Senior Patient Care Coordinator.
Crash Course 3 – CJC-1295/Ipamorelin
Welcome to The Optimization Academy Crash Course Series with Dr. Greg Jones! I wanted to create short videos and podcasts where I can take a deep dive into frequently asked questions and topics that my patients and myself find complicated or intriguing.
Peptides CJC 1295 + Ipamorelin Benefits | Best Growth Hormone Releasing Peptides | Dr. Paziotopoulos
What are the most effective peptides for growth? Is a mixture of peptides CJC 1295 + Ipamorelin the best for muscle growth? What is the best growth hormone-releasing peptide? What results and benefits you can expect by taking them.
