SEENERGIE
Unleash Human Potential
SS-31
Known for improving mitochondrial functions, giving cardioprotective, neuroprotective, anti-aging effects.
Active ingredient:
16 amino acids
Molecular formula:
C32H49N9O5
Molecular weight:
639.79 g/mol
Intake:
Injection
SS-31
Active ingredient:
16 amino acids
Molecular formula:
C32H49N9O5
Molecular weight:
639.79 g/mol
Intake:
Injection
What is
SS-31
SS-31 is a class of cell-permeable small peptides, which selectively resides on the inner mitochondrial membrane and possesses intrinsic mitochondrial protective capacities. Specifically, SS-31 (also known as MTP-131) is a water-soluble mitochondria-targeting peptide that attenuates mitochondrial reactive oxygen species production and cytochrome c release. This peptide has been shown to reverse decline in diabetes, attenuate transverse aortic constriction-induced pulmonary arterial hypertension and heart failure, and rapidly rejuvenates oxidative phosphorylation in aged mice.
Benefits
- Weight loss
- Enhances energy levels
- Greater resistance to metabolic stress
- Improves healthspan and lifespan
Protocols
- Content and Potency
Provided as a 10mg lyophilized vial
- Suggested Dosage
- Initiation: SS-31 therapy is initiated to provide mitochondrial protection and improve cellular function.
- Initial Dose: Begin with 5 mg (0.5 ml or 50 units) subcutaneously once daily (SCOD) to assess tolerance and minimize potential side effects.
- Titration: If well tolerated, the dose may be increased to 10 mg (1 ml or 100 units) subcutaneously once daily after the initial period of assessment.
- Maintenance: Maintain the dose at 5-10 mg (0.5-1 ml or 50-100 units) subcutaneously once daily for ongoing mitochondrial protection and cellular function improvement.
- Duration: SS-31 is administered once daily.
- Ongoing: 5-10 mg (0.5-1 ml or 50-100 units) of SS-31 once daily
*Provided as a standard protocol, dose may vary depending on the condition of the patient.
*The dosage of SS-31 may be adjusted based on the individual’s response, medical history, and specific treatment goals.
- Restrictions
- Known hypersensitivity to SS-31 or any component of the formulation.
- Not recommended for use during pregnancy or breastfeeding unless specifically advised by a healthcare provider.
- Requirements
- Regular monitoring of cellular and mitochondrial function to assess the effectiveness of the treatment.
- Periodic blood tests to check for any adverse effects and to adjust the treatment as necessary.
Procedure
- SS-31
Reconstitution
- Draw 1 ml of sterile water for injection into a syringe.
- Inject the sterile water into a vial containing 10 mg of SS-31 peptide.
- Gently swirl the vial until the peptide is fully dissolved.
- Administration
- Remove the cap from a tuberculin syringe.
- Draw the reconstituted SS-31 solution into the syringe to the required dosage (0.5 ml or 50 units for 5 mg, 1 ml or 100 units for 10 mg).
- Clean the selected injection site with an alcohol swab.
- Pinch the sanitized skin and insert the needle at a 90-degree angle.
- Administer the injection subcutaneously.
- For next usage
- Store the remaining SS-31 solution in the refrigerator at 2-8°C.
- Before the next use, clean the vial top with an alcohol swab.
- Use a new syringe for each administration.
- Ensure to rotate injection sites (abdomen, thigh, or upper arm) to minimize skin irritation. )
Clinical Research
Study:
SS-31 Peptide for Weight Loss
Source:
PLOS ONE, Journal of Neuroinflammation, Frontiers, Pharmaceutical Research
Results:
SS-31, also known as Elamipretide or Bendavia, is a synthetic peptide that targets and protects mitochondria, improving mitochondrial function and reducing oxidative stress. Research has demonstrated its potential benefits in various health conditions, including weight management and metabolic health.
Studies indicate that SS-31 can positively affect weight loss and metabolic health by improving mitochondrial efficiency and reducing oxidative stress. Improved mitochondrial function leads to enhanced energy expenditure and fat metabolism, which are critical factors in weight management.
In animal models, SS-31 has been shown to reduce fat accumulation and improve insulin sensitivity. Chronic administration of SS-31 in high-fat diet-induced obese mice resulted in significant weight reduction, improved glucose tolerance, and decreased levels of inflammatory markers associated with obesity and metabolic syndrome.
PLOS ONE, 2023, Journal of Neuroinflammation, 2023, Frontiers, 2023, Pharmaceutical Research, 2023
Articles
The mitochondria are being discovered to be more than just “the powerhouse of the cell”
Mitochondria have recently entered center stage as the major regulator of life and death in the cell oxidative damage to mitochondria can result in cytochrome c release into the cytosol and activation of the caspase cascade, leading to apoptosis ,Cell death induced by mitochondrial oxidative damage plays an important role in numerous clinical disorders, including […]
Peptide Therapy: SS-31, The Mitochondria Peptide
The mitochondria are the powerhouse of the cell. This basically means the mitochondria are responsible for producing the energy that the cell needs in order to function. In order for any cell in our body to perform at its best, we need our mitochondria to function. In this article, you will learn about a peptide […]
Doctor's Reviews
SS-31 as a Mitochondrial Protectant in the Treatment of Tendinopathy
SS-31 as a Mitochondrial Protectant in the Treatment of Tendinopathy Xueying Zhang, MD, PhD
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Discover the amazing potential of SS-31, a new peptide in town! Learn how it can improve brain function, joint health, and fight inflammation. #Peptides #Biohacking #Antioxidant #BrainFunction #JointHealth #Inflammation #HealthTips
SS-31 Overview by Core Medical Group Physician, Dr. Drew Coleman
A breakdown of Peptide SS-31 and all the amazing effects you can benefit from.
